Application Notes

High-Throughput Production of Matrix-Embedded Multicellular Tumour Spheroids by Drop-on-Demand 3D Bioprinting

This application note provides an overview of the creation of breast and prostate multicellular tumour spheroids using RASTRUM™.

Cell Retrieval from RASTRUM™ 3D Bioprinted Hydrogels Enables High-Quality RNA and Protein Extraction

This application note demonstrates how cells encapsulated in RASTRUM™ Matrices can be easily retrieved to enable investigations into gene and protein expression.

Brightfield and Fluorescent Imaging of RASTRUM™ 3D Bioprinted Cell Models

This application note demonstrates the compatibility of imaging methods with 3D cell models created using RASTRUM™.

Printable and Tunable 3D Cell Culture Environments using RASTRUM™ Synthetic ECM Hydrogels

This application note provides an overview of the utility and tunability of RASTRUM™ matrix systems.

Drop-on-Demand Printing Technology of the RASTRUM™ 3D Cell Culture Platform

This application note details the key printing features offered by RASTRUM™.


Cell Retrieval from RASTRUM™ Matrices

This protocol outlines how the enzymatic-based RASTRUM™ Cell Recovery Solution can be used to extract 3D cell models encapsulated in RASTRUM™ Matrices for use in downstream applications.

In Situ Viability Analysis of RASTRUM™ Bioprinted 3D Cell Models

This protocol outlines a method to assess viability of 3D Cell Models created with RASTRUM™ using fluorescent dyes for distinguishing live and dead cells via fluorescence microscopy.

In Situ Immunofluorescence Analysis of RASTRUM™ Bioprinted 3D Cell Models

This protocol outlines a method to analyse protein expression via immunofluorescence in 3D cell models created with RASTRUM™.

News and Press Releases

Inventia wins Australia’s Good Design Award of the Year for RASTRUM™ 3D bioprinter

Read the article by the 3D Printing Media Network here.

The prestigious Good Design Award of the Year was awarded to the revolutionary RASTRUM™ 3D Bioprinter that is helping to fight cancer by building 3D cell structures which are then used to test a range of therapies.

This 3D printer produces living cancer cells so scientists can test drugs on the real thing

Read the article by Fast Company here.

Inventia Life Sciences' RASTRUM™—a winner of Fast Company’s 2020 World Changing Ideas Awards—uses the technology of an inkjet printer to create lifelike human cell structures so biologists can see how drugs work on real cells.

RASTRUM™ - the 3D Printer of Living Cells, Honored in Annual Awards by Leading Business Magazine

Read the article by PRWeb here.

RASTRUM™ has taken out the top prize in the Experimental category. RASTRUM™ prints human cells into living tissue models to supercharge research into cancer and other diseases using revolutionary drop-on-demand technology.

Inventia Life Science Empowers Researchers to Rapidly Scale 3D Cell Culture

Read the article by here.

Sydney based start-up company, Inventia Life Science has developed digital bioprinting technology for fast, scalable, and reproducible printing of 3D cell models.

Associate Professor Kieran Scott: Growing 3D brain cancer organoids – the new frontier in cancer research

Read the article by the Centre of Oncology Education and Research Translation (CONCERT) here.

When Associate Professor Kieran Scott goes to sleep at night, he dreams of fighting cancer… and winning. When he awakens, he goes to work, excited to be working on projects which are bringing his dreams closer to reality.

Product Videos

The Revolutionary RASTRUM™ 3D Cell Culture Platform

This short video provides an overview of the RASTRUM™ 3D Cell Culture Platform from Inventia Life Science. RASTRUM™ is built for 3D cell biology, accelerating drug discovery and biomedical research with the power of digital bioprinting.

The RASTRUM™ 3D Cell Culture Platform Workflow

This short video demonstrates the typical workflow for generating RASTRUM™ 3D cell models. RASTRUM™ is a complete and efficient plug and play platform, requiring minimal user involvement to create complex 3D cell models in a simple way.


Interview with Dr Julio Ribeiro - Fast Company World Changing Ideas Award

This short video interview with Dr Julio Ribeiro, co-founder and CEO of Inventia Life Science, speaks about RASTRUM being honoured by Fast Company in the 2020 World Changing Ideas Awards in the Experimental Category.

Podcast with Dr Julio Ribeiro speaking to Mark Bouris in his ‘The Mentor’ Podcast series

This podcast featured in Mark Bouris’ ‘The Mentor’ series will take you on the Inventia Life Science journey - from initial idea to the internationally acclaimed RASTRUM™ 3D Cell Culture Platform.
**Podcast may not be accessible outside Australia**

Frequently Asked Questions

Platform FAQs

Click here to download the Frequently Asked Questions related to the RASTRUM™ Cell Culture Platform.

Hydrogel FAQs

Click here to download the Frequently Asked Questions related to RASTRUM™ Hydrogels.

Applications FAQs

Click here to download the Frequently Asked Questions related to RASTRUM™ Applications.

Laboratory Requirements FAQs

Click here to download the Frequently Asked Questions related to RASTRUM™ Laboratory Requirements.

Supplementary Literature

Peer-Reviewed Publications

1. Heinrich MA, Liu W, Jimenez A, Yang J, Akpek A, Liu X, Pi Q, Mu X, Hu N, Schiffelers RM, Prakash J, Xie J, Zhang YS. 2019. 3D Bioprinting: from Benches to Translational Applications. Small. 15:1805510 - Link

2. Gudapati H, Dey M, Ozbolat I. 2016. A comprehensive review on droplet-based bioprinting: Past, present and future. Biomaterials. 102:20-42 - Link

3. Holle AW, Young JL, Spatz JP. 2016. In vitro cancer cell-ECM interactions inform in vivo cancer treatment. Advanced Drug Delivery Reviews. 97:270-279 - Link

4. Nguyen EH, Daly WT, Le NNT, Farnoodian M, Belair DG, Schwartz MP, Lebakken CS, Ananiev GE, Saghiri MA, Knudsen TB et al. 2017. Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion. Nature Biomedical Engineering. 1:0096 - Link

5. Antoni D, Burckel H, Josset E, Noel G. 2015. Three-Dimensional Cell Culture: A Breakthrough in Vivo. International Journal of Molecular Sciences. 16(3):5517-5527 - Link

6. Langhans SA. 2018. Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning. Frontiers in Pharmacology. 9:6 - Link