High-Throughput Phenotypic Screening using RASTRUM™ Advanced Cell Models

This application note provides an overview of cell painting-based phenotypic screening of advanced cell models using RASTRUM™ with high-content confocal imaging and machine learning.

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Highlights

In this application note, the RASTRUM™ Platform, developed by Inventia Life Science, has been combined with Operetta CLS™ high-content analysis system and customised machine learning algorithms to demonstrate the utility of cell painting-based phenotypic screening of advanced cell models in synthetic matrices with U-87MG glioblastoma cells.