Traditional approaches to personalized therapy screening are often slow, variable, and difficult to scale. In this application note, we demonstrate how the RASTRUM™ Allegro platform, combined with OncoPro™ Tumoroid Cell Lines and Culture Media from Thermo Fisher Scientific, enables a rapid and reproducible framework for evaluating novel precision medicine strategies.
Using patient-derived colorectal cancer tumoroids, we establish a workflow that maintains subtype-specific molecular features, supports multiplexed drug testing, and generates actionable therapeutic insights—all in just 8 weeks. With seamless integration of RASTRUM Cloud and matrix optimization tools, this approach offers a scalable and translationally relevant alternative to traditional preclinical models.