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Reproducibility: Biological systems are inherently variable. Generating consistent, high-throughput 3D cell models requires precise control over cell placement, matrix composition, and environmental factors.
Cell viability: Unlike plastic or metal printing, bioprinting involves living cells that can be damaged by shear stress, temperature fluctuations, and mechanical forces during the printing process.
Scalability: Many bioprinting methods are slow or labor-intensive, making it difficult to generate the large-scale, high-throughput cell models required for drug discovery and disease research.
Biomaterial: Developing bioinks that replicate the mechanical, chemical, and biological properties of human tissues while supporting cell growth, adhesion, and differentiation, and maintaining printability.

Use our resource hub to learn more about RASTRUM™ for your 3D cell culture needs and explore peer-reviewed publications powered by RASTRUM.

Our in-house curated application notes highlight the applicability and capability of the RASTRUM Platform.

Discover how the platform can be utilized for a particular application to support impactful scientific research.

Drug repurposing screen targeting PARP identifies cytotoxic activity of efavirenz in high-grade serous ovarian cancer View Publication A comparative analysis of 2D and 3D experimental data for the identification of the parameters of computational models View Publication Effect of 3D-bioprinted droplet impact dynamics on a pre-printed soft hydrogel matrix View Publication Adipose-Derived Stem Cells Spontaneously Express Neural Markers When Grown in a PEG-Based 3D Matrix View Publication Preclinical study of synergistic combination of sacituzumab govitecan and talazoparib in ovarian cancer models View Application Resource Bioprinting for biologists: What researchers need to know about reproducible 3D cell models View Blog Chemotherapeutic Potential of Chlorambucil-Platinum(IV) Prodrugs against Cisplatin-Resistant Colorectal Cancer Cells View Publication Protocol to create phenotypic primary human hepatocyte cultures using the RASTRUM 3D cell model platform View Publication Anticancer Effect of PtIIPHENSS, PtII5MESS, PtII56MESS and Their Platinum(IV)-Dihydroxy Derivatives against Triple-Negative Breast Cancer and Cisplatin-Resistant Colorectal Cancer View Publication FK506 binding protein like, FKBPL, as a novel therapeutic target in 2D and 3D bioprinted, models of cardiac fibrosis View Publication

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