The RASTRUM™ platform is being applied to accelerate drug discovery and biomedical research.
The power to place cell and matrix components in precise 3D constructs opens up new possibilities in fundamental explorative biology. For probing specific cell-cell or cell-matrix interactions, working in low or medium throughput, RASTRUM™ enables experiments not previously possible.
Create complex 3D cell models with multiple cell and/or matrix components
Probe specific cell-cell or cell-matrix interactions in a controlled and quantitative way
Open your experimental design to rapid testing of multiple variables in 3D
The speed and reproducibility of 3D cell model creation using RASTRUM™ is a step-change for medium to high-throughput drug discovery and screening, enabling you to move confidently to implementing 3D models in your pre-clinical pipeline.
Creation of 3D cell models an order of magnitude faster than manual methods
Unprecedented reproducibility well-to-well, day-to-day and site-to-site
Better quantitative 3D analysis due to controlled structure-readout correlation
The potential to screen a range of drugs or combinations against an individual patient’s tumour cells in vitro, combined with genomic analysis, is bringing a paradigm shift in patient care.
Work confidently with low numbers of patient-derived cells without loss
Rapidly screen an optimal matrix environment for an individual tumour
Efficient patient-to-3D workflow for rapid screening capability
3D multicellular tumour spheroid models that resemble small tumours and micrometastasesRead more
Single multicellular tumour spheroids with similar physiological traits to solid tumoursRead more
3D migration / invasion assays
Cell migration models for studying processes such as metastasis and inflammationRead more
Inclusion of stromal cell types to study tumour initiation, proliferation and metastasisRead more
Combination of immune cells and cancer cells to better mimic patient tumour responsesRead more
Co-culture of multiple neuronal cell types for enhanced neural network formation and activityRead more