The RASTRUM™ platform is being applied to accelerate drug discovery and biomedical research.

Fundamental biology

The power to place cell and matrix components in precise 3D constructs opens up new possibilities in fundamental explorative biology. For probing specific cell-cell or cell-matrix interactions, working in low or medium throughput, RASTRUM™ enables experiments not previously possible.

Benefits —

  • Create complex 3D cell models with multiple cell and/or matrix components

  • Probe specific cell-cell or cell-matrix interactions in a controlled and quantitative way

  • Open your experimental design to rapid testing of multiple variables in 3D

Drug discovery

The speed and reproducibility of 3D cell model creation using RASTRUM™ is a step-change for medium to high-throughput drug discovery and screening, enabling you to move confidently to implementing 3D models in your pre-clinical pipeline.

Benefits —

  • Creation of 3D cell models an order of magnitude faster than manual methods

  • Unprecedented reproducibility well-to-well, day-to-day and site-to-site

  • Better quantitative 3D analysis due to controlled structure-readout correlation

Personalised screening

The potential to screen a range of drugs or combinations against an individual patient’s tumour cells in vitro, combined with genomic analysis, is bringing a paradigm shift in patient care.

Benefits —

  • Work confidently with low numbers of patient-derived cells without loss

  • Rapidly screen an optimal matrix environment for an individual tumour

  • Efficient patient-to-3D workflow for rapid screening capability

Our models

Tumour spheroids

3D multicellular tumour spheroid models that resemble small tumours and micrometastases

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Single spheroid

Single multicellular tumour spheroids with similar physiological traits to solid tumours

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3D migration / invasion assays

Cell migration models for studying processes such as metastasis and inflammation

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Cancer co-culture

Inclusion of stromal cell types to study tumour initiation, proliferation and metastasis

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Immuno-oncology models

Combination of immune cells and cancer cells to better mimic patient tumour responses

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Neural co-culture

Co-culture of multiple neuronal cell types for enhanced neural network formation and activity

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Compatible with a range of breast tissue cell types

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Compatible with a range of lung tissue cell types

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Compatible with a range of neural tissue cell types

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Compatible with a range of liver tissue cell types

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Compatible with a range of skin tissue cell types

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Compatible with a range of pancreas tissue cell types

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Compatible with a range of prostate tissue cell types

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Ready to shift to better 3D models?

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