The RASTRUM™ platform is being applied to accelerate drug discovery and biomedical research.

Our areas of interest

Breast

Compatible with a range of breast tissue cell types

Lung

Compatible with a range of lung tissue cell types

Brain

Compatible with a range of neural tissue cell types

Liver

Compatible with a range of liver tissue cell types

Skin

Compatible with a range of skin tissue cell types

Pancreas

Compatible with a range of pancreas tissue cell types

Prostate

Compatible with a range of prostate tissue cell types

Stem (Developmental)

Compatible with a range of stem cell types

Ovaries

Compatible with a range of ovarian tissue cell types

Fundamental biology

The power to place cell and matrix components in precise 3D constructs opens up new possibilities in fundamental explorative biology. For probing specific cell-cell or cell-matrix interactions, working in low or medium throughput, RASTRUM™ enables experiments not previously possible.

Benefits —

Create complex 3D cell models with multiple cell and/or matrix components

Probe specific cell-cell or cell-matrix interactions in a controlled and quantitative way

Open your experimental design to rapid testing of multiple variables in 3D

Drug discovery

The speed and reproducibility of 3D cell model creation using RASTRUM™ is a step-change for medium to high-throughput drug discovery and screening, enabling you to move confidently to implementing 3D models in your pre-clinical pipeline.

Benefits —

Creation of 3D cell models an order of magnitude faster than manual methods

Unprecedented reproducibility well-to-well, day-to-day and site-to-site

Better quantitative 3D analysis due to controlled structure-readout correlation

Personalised screening

The potential to screen a range of drugs or combinations against an individual patient’s tumour cells in vitro, combined with genomic analysis, is bringing a paradigm shift in patient care.

Benefits —

Work confidently with low numbers of patient-derived cells without loss

Rapidly screen an optimal matrix environment for an individual tumour

Efficient patient-to-3D workflow for rapid screening capability

Our models

Tumour spheroids

3D multicellular tumour spheroid models that resemble small tumours and micrometastases

3D migration / invasion assays

Cell migration models for studying processes such as metastasis and inflammation

Cancer co-culture

Inclusion of stromal cell types to study tumour initiation, proliferation and metastasis

Immuno-oncology models

Combination of immune cells and cancer cells to better mimic patient tumour responses

Neural co-culture

Co-culture of multiple neuronal cell types for enhanced neural network formation and activity

Ready to shift to better advanced cell models?