The RASTRUM™ platform is being applied to accelerate drug discovery and biomedical research.

Our Areas of Interest

Breast

Compatible with a range of breast tissue cell types

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Lung

Compatible with a range of lung tissue cell types

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Brain

Compatible with a range of neural tissue cell types

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Liver

Compatible with a range of liver tissue cell types

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Skin

Compatible with a range of skin tissue cell types

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Pancreas

Compatible with a range of pancreas tissue cell types

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Prostate

Compatible with a range of prostate tissue cell types

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Stem (Developmental)

Compatible with a range of stem cell types

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Ovaries

Compatible with a range of ovarian tissue cell types

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Fundamental biology

The power to place cell and matrix components in precise 3D constructs opens up new possibilities in fundamental explorative biology. For probing specific cell-cell or cell-matrix interactions, working in low or medium throughput, RASTRUM™ enables experiments not previously possible.

Benefits —

  • Create complex 3D cell models with multiple cell and/or matrix components

  • Probe specific cell-cell or cell-matrix interactions in a controlled and quantitative way

  • Open your experimental design to rapid testing of multiple variables in 3D

Drug discovery

The speed and reproducibility of 3D cell model creation using RASTRUM™ is a step-change for medium to high-throughput drug discovery and screening, enabling you to move confidently to implementing 3D models in your pre-clinical pipeline.

Benefits —

  • Creation of 3D cell models an order of magnitude faster than manual methods

  • Unprecedented reproducibility well-to-well, day-to-day and site-to-site

  • Better quantitative 3D analysis due to controlled structure-readout correlation

Personalised screening

The potential to screen a range of drugs or combinations against an individual patient’s tumour cells in vitro, combined with genomic analysis, is bringing a paradigm shift in patient care.

Benefits —

  • Work confidently with low numbers of patient-derived cells without loss

  • Rapidly screen an optimal matrix environment for an individual tumour

  • Efficient patient-to-3D workflow for rapid screening capability

Our models

Tumour spheroids

3D multicellular tumour spheroid models that resemble small tumours and micrometastases

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3D migration / invasion assays

Cell migration models for studying processes such as metastasis and inflammation

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Cancer co-culture

Inclusion of stromal cell types to study tumour initiation, proliferation and metastasis

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Immuno-oncology models

Combination of immune cells and cancer cells to better mimic patient tumour responses

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Neural co-culture

Co-culture of multiple neuronal cell types for enhanced neural network formation and activity

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Ready to shift to better 3D models?

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