Fundamental biology
The power to place cell and matrix components in precise 3D constructs opens up new possibilities in fundamental explorative biology. For probing specific cell-cell or cell-matrix interactions, working in low or medium throughput, RASTRUM™ enables experiments not previously possible.
Benefits —
Create complex 3D cell models with multiple cell and/or matrix components
Probe specific cell-cell or cell-matrix interactions in a controlled and quantitative way
Open your experimental design to rapid testing of multiple variables in 3D
Drug discovery
The speed and reproducibility of 3D cell model creation using RASTRUM™ is a step-change for medium to high-throughput drug discovery and screening, enabling you to move confidently to implementing 3D models in your pre-clinical pipeline.
Benefits —
Creation of 3D cell models an order of magnitude faster than manual methods
Unprecedented reproducibility well-to-well, day-to-day and site-to-site
Better quantitative 3D analysis due to controlled structure-readout correlation
Personalised screening
The potential to screen a range of drugs or combinations against an individual patient’s tumour cells in vitro, combined with genomic analysis, is bringing a paradigm shift in patient care.
Benefits —
Work confidently with low numbers of patient-derived cells without loss
Rapidly screen an optimal matrix environment for an individual tumour
Efficient patient-to-3D workflow for rapid screening capability
Our models
Tumour spheroids
3D multicellular tumour spheroid models that resemble small tumours and micrometastases
Read moreSingle spheroid
Single multicellular tumour spheroids with similar physiological traits to solid tumours
Read more3D migration / invasion assays
Cell migration models for studying processes such as metastasis and inflammation
Read moreCancer co-culture
Inclusion of stromal cell types to study tumour initiation, proliferation and metastasis
Read moreImmuno-oncology models
Combination of immune cells and cancer cells to better mimic patient tumour responses
Read moreNeural co-culture
Co-culture of multiple neuronal cell types for enhanced neural network formation and activity
Read more