Create a relevant microenvironment with predictable matrix and model performance that gives you better data.
The matrix
Choosing a suitable extracellular matrix mimic is critical to the success of any advanced cell model. Given the many roles of matrix in guiding cellular behaviour and response, no one matrix can suit all applications.
RASTRUM™ Matrices are tuned to each cell type and research question by modifying:
Stiffness
Tunable stiffness to provide a physiologically relevant environment
Adhesion peptides
Including the core peptide sequences that mediate integrin binding (i.e. RGD, IKVAV, YIGSR)
Full-length proteins
Enriched in natural extracellular matrices (i.e. laminin and fibronectin)
MMP-sensitive sites
To enable cleavage of the matrix by cell-secreted proteases
No matter the formulation, RASTRUM™ Matrices provide several benefits over other systems:
No batch-to-batch variation
Printable with instant gelation at room temperature
Permeable to antibodies, growth factors and small molecules
Fully transparent with no auto-fluorescence
Dissolvable to enable cell extraction