RASTRUM™ Matrix

The matrix

Choosing a suitable extracellular matrix mimic is critical to the success of any advanced cell model. Given the many roles of matrix in guiding cellular behaviour and response, no one matrix can suit all applications.

RASTRUM™ Matrices are tuned to each cell type and research question by modifying:

Stiffness

Tunable stiffness to provide a physiologically relevant environment

Adhesion peptides

Including the core peptide sequences that mediate integrin binding (i.e. RGD, IKVAV, YIGSR)

Full-length proteins

Enriched in natural extracellular matrices (i.e. laminin and fibronectin)

MMP-sensitive sites

To enable cleavage of the matrix by cell-secreted proteases