Phenotypic 3D cell models: Benefits and how to get started

Phenotypic 3D cell models: Benefits and how to get started

This comprehensive guide will provide an overview of the benefits of phenotypic 3D cell models from a drug discovery perspective. Discover the main considerations on transitioning from 2D to 3D and how to get valuable insights from your 3D cell models
Back to resources / Whitepapers

Introduction

The shift from 2D to 3D cell cultures for drug discovery

Traditionally, 2D cell cultures have been used as in vitro models in drug screening studies due to their simplicity and scalability. However, 2D cell models do not recapitulate the complexity of in vivo biology. This means that a large number of drug candidates fail when they move to human clinical trials. Phenotypic models could provide deeper and more relevant insights in drug discovery.

PHENOTYPIC 3D CELL MODELS: BENEFITS AND HOW TO GET STARTED